PROBIOTICS CAN HELP PREVENT (OR ATTENUATE) the negative changes in the composition of gut microbes associated with antibiotic treatment. Today we look at adding probiotics to antibiotics.
Have you ever had antibiotic-induced diarrhea? I mean passing loose, watery stools at least three times daily after taking antibiotic medicines to treat bacterial infections.
Approximately one in five individuals who take antibiotics develop antibiotic-associated diarrhea. Antibiotic-associated diarrhea is likely to start a week or so after antibiotic initiation. Occasionally, diarrhea and other symptoms do not emerge until days or weeks after the completion of the antibiotic course.
Fortunately, diarrhea is typically mild, self-limited, and requires no treatment. Fortunately, the gastrointestinal upset usually resolves within a few days of discontinuing the antibiotic. The antibiotic may need to be switched or discontinued for those with more serious GI problems.
Antibiotic-associated diarrhea is likely to begin about a week after you start taking an antibiotic. However, diarrhea and other symptoms sometimes don’t appear until days or weeks after you’ve finished antibiotic treatment.
Clostridioides difficile (C. diff)
I would be remiss if I did not mention C. difficile. These toxin-making bacteria can cause serious antibiotic-related diarrhea or more frequent bowel movements. In addition to causing loose stools and more-frequent bowel movements, C. difficile infection can cause:
- Severe diarrhea and dehydration
- Lower abdominal pain and cramping
- Low-grade fever
- Nausea
- Loss of appetite
Most cases of C. diff occur when someone has been taking antibiotics (or not long after completing an antibiotic course). While the infection can affect anyone, risk factors include:
- Age 65 or older
- A recent hospital or nursing home stay
- A weakened immune system (for example, in those with HIV/AIDS, cancer, or organ transplant patients taking immunosuppressive drugs)
- Prior infection with C. diff or known exposure to the germs
Here are some disturbing statistics from the US Centers for Disease Control (CDC): C. diff causes nearly half a million infections in the United States annually. Of those who get an infection, one in six will get it again in the subsequent two to eight weeks. One in 11 over 65 will die of symptoms related to a C. diff infection within one month.
Those with C. diff are contagious, so please wash your hands with soap and water each time you use the bathroom and before you eat. If you have diarrhea, use a separate bathroom if possible. Finally, take showers and wash with soap.
Please call your healthcare provider immediately if you have serious symptoms of antibiotic-associated diarrhea. These symptoms are common to several conditions, so you may need tests — for example, stool or blood— to determine the cause.
While antibiotics are an important tool for battling potentially life-threatening bacteria, the drugs can disrupt the composition and function of the gut microbiome. More specifically, antibiotics can drop the abundance and diversity of gut bacteria, opening the door to infection by bad, pathogenic bacteria.
What is the microbiome?
Here is what I previously wrote about the microbiome:
“The microbiome, the collection of bacteria, fungi, and viruses that live in and on our bodies, is a component of our immune system. The microbiome is essential to the defense systems of our bodies.
We have approximately 100 trillion microbes — including bacteria, fungi, and viruses — primarily found in the gastrointestinal system, our skin, and other body parts.
I have a new word for you: Dysbiosis, a change in the microbiome’s composition, diversity, or metabolites from a healthy pattern to one associated with a disease. Antibiotics can be a cause. Replacing microorganisms (via fecal transplants) can be an effective management option for some problems, such as inflammatory bowel disease and certain recurrent infections associated with antibiotic use.
What does this have to do with you? Dysbiosis plays a role in diverse conditions, including type 2 diabetes, obesity, asthma, food allergy, and atopic dermatitis. The gut microbiome is thus an attractive target for intervention. Some have found success in managing type 2 diabetes with gut microbiome manipulation.
I’ll bet you didn’t know that the microbiota can weigh upwards of two kilograms. A growing body of evidence points to the microbiome as essential to metabolic function, digestion, and resisting infection. Your genes, environment, and medicines can influence gut microbiota.”
Antibiotics and the microbiome
Some have hailed antibiotics as miracle drugs that have revolutionized medicine since their introduction more than a hundred years ago. By effectively treating infectious bacterial diseases, these drugs have ushered in an era with far fewer medical issues and deaths.
With antibiotic use has come increasing threats, including antibiotic resistance and potential direct harm to human health. Animal studies remind us that gut microbiome disruption (secondary to antibiotics) can have long-lasting harmful effects, including a higher risk of allergies and obesity.
To learn more about adding probiotics to antibiotics, please hop over to the full article by using this free Medium.com link:
Thank you. One more thing:
https://newcancerinfo.com/2022/11/19/are-your-probiotics-safe/
The information I provided in this blog is for educational purposes only and does not substitute for professional medical advice. Please consult a medical professional or healthcare provider if you seek medical advice, diagnoses, or treatment. I am not liable for risks or issues associated with using or acting upon the information in this blog.
