• Home
  • Blog
  • About
  • Shop
  • Nav Social Icons

  • Skip to primary navigation
  • Skip to main content
  • Skip to primary sidebar
  • Skip to footer
  • Home
  • About
  • Shop
  • Contact
  • Body
  • Mind
  • Social
  • Mobile Menu Widgets

    Connect

    Search

Dr. Michael Hunter's Wellness

What You Need to Know to Optimize Your Health

  • Body
  • Mind
  • Social
You are here: Home / Wellness / Missing Teeth and Cancer Risk
selective photo of gray shark

Missing Teeth and Cancer Risk

March 16, 2024 · In: Wellness


MISSING TEETH AT BIRTH IS LINKED TO CANCER RISK. A new study from Denmark suggests that congenital tooth loss is linked to cancer risk. 

This essay will briefly explore this hypothesis-generating finding.

Speaking to Helio, study author Sage E. Eiset offers this take:

“The hypothesis is not new but has not yet been investigated in a population-based setting. In Denmark, we have several population-based registries with many years of high-quality data, including a public dental registry. This was a unique opportunity to investigate the tooth agenesis–cancer hypothesis.”

Let’s look at the new and provocative study.

Background

Tooth loss is a common condition that affects millions of people around the world, and cancer is a major health concern that affects millions of people each year. 

Previous research has suggested a link between missing teeth from birth and cancer risk, but this link has not yet been thoroughly investigated in a population-based setting. 

A new study from Denmark builds on previous research to shed new light on the potential link between missing teeth at birth and cancer risk.

Study Details

Researchers in Denmark looked at records of people born between 1977 and 2018 to see if there was a link between missing teeth at birth and certain types of cancer. 

The idea is brilliant.

They collected information from various databases on missing teeth (excluding wisdom teeth) and cancer diagnoses.

Sunset, as scene from a building in Copenhagen. The windows extend floor to ceiling in this curved structure.
Photo by Here To Travel on Unsplash

The study involved over 2.5 million individuals, with just over 2.8 percent having missing teeth at birth and 1.1 percent being diagnosed with cancer at a young age. 

Out of those, 778 people had both missing teeth at birth and cancer.

Study Results

The study found that children aged 1 to 3 years with missing teeth at birth were more likely to develop certain cancers, including the following types:

A 2D bar graph showing the relative increase in cancer for those ages 1 to 3.
  • leukemia (a type known as acute myeloid leukemia; 3.5 times higher risk)
  • neuroblastoma (4.2 times)
  • kidney tumors (4.6 times)
  • liver cancer (7.1 times)
  • muscle cancer (8.8 times)
Photo by Ben White on Unsplash

Children aged 3 to 6.

A 2D bar char showing the relative increases in cancer for those ages 3 to 6 who have missing teeth at birth.

Children aged 3 to 6 had a higher risk of muscle cancer (rhabdomyosarcoma risk increased 3.5 times) and leukemia (acute myeloid leukemia risk increased 3.8 times).

Children aged 10 to 20.

A 2D bar char showing the relative increases in cancer for those ages 10 to 20 who have missing teeth at birth.

Between 10 to 20 years old, individuals with missing teeth had an increased bone cancer risk. Osteosarcoma, a type of bone cancer, risk increased by 2.2 times.

Children aged 20 and older.

A 2D bar graph showing the relative increase in cancer for those ages 20 years and older.

Finally, young adults aged 20 to 30 had a higher chance of developing appendix (2.5 times) and bladder cancers (3.4 times), while those aged 30 to 40 had a 2.8-fold increase in colorectal cancer risk.

My Take – Missing Teeth and Cancer Risk

Do you have a missing tooth (tooth agenesis)?

Tooth agenesis is quite common. On the other hand, the study revealed few cancer cases.

Even if your risk is up to 8.8 times higher for muscle cancer, it is very unlikely you will ever get it.

There are only 400 to 500 children who develop muscle cancer each year.

Why Is There a Tooth Agenesis: Cancer Connection?

The findings may be erroneous; that is, they occurred by chance.
Still, some findings are biologically explainable.

Did you know tooth development is a complex process involving several signaling pathways? Fascinating, right?

These pathways include Wnt, BMP, FGF, Shh, Eda, and others. It’s amazing how many intricate mechanisms are at play to give us our pearly whites!

Multicolored genes as seen in a photomicrograph.
Photo by National Cancer Institute on Unsplash

For example, the AXIN2 gene is connected to tooth anomalies and colon cancer.

Limitations of the Study

The study is registration-based. 

While this approach allowed the researchers to build a massive database, it did not allow the establishment of causality.

The findings may be erroneous; that is, they occurred by chance.

Finally, if a very young child had previous cancer therapy, that could impact oral health.

Takeaway Message – Missing Teeth and Cancer Risk

A recent study from Denmark found that missing teeth (excluding wisdom teeth) at birth may be linked to an increased risk of certain cancers.

The study, which involved over 2.5 million individuals, found that children aged 1 to 3 years with missing teeth were more likely to develop acute myeloid leukemia, neuroblastoma, kidney tumors, liver cancer, and muscle cancer. 


While the study suggests a possible link between missing teeth and cancer risk, it is important to note that the overall risk of developing these cancers is still quite low.

Thank you for reading “Missing Teeth and Cancer Risk.”

Reduce Your Cancer Risk Through Lifestyle

By: Dr. Michael Hunter · In: Wellness · Tagged: cancer causes, childhood cancer, health, teeth, teeth and cancer, tooth agenesis and cancer

you’ll also love

🧠 The Surprising Mental Medicine You Already Own
The Grocery Store Aisle Is Quietly Killing Us
💪 Why Doing Less Builds More Muscle (At Any Age)

Join the List

Stay up to date & receive the latest posts in your inbox.

Next Post >

Vitamin D: Yea or Nay?

Primary Sidebar

Meet Dr. Hunter

Meet Dr. Hunter

Your go-to source for all things wellness. I am Michael Hunter. I practice radiation oncology in the Seattle area and have a particular interest in health. I am delighted that you have joined me here. Thank you.

Read More

Connect

join the list

Featured Posts

photo of man wearing hooded jacket in front of body of water

This Raises Prostate Cancer Risk by Nearly Half

woman in gray tank top lying on bed

Melatonin is Not a Sleeping Pill

The Beams Save Lives — But THIS Saves More

Categories

  • Body
  • Mind
  • Social

Search

Archives

Follow Along

@michaelhuntermd

thebreastcancerdoctor

#Stanford2021 #tyhunter #Stanford2021 #tyhunter
#stanforduniversity #graduation #tyhunter #stanforduniversity #graduation #tyhunter
Hope you too are having a joy-filled weekend! Hope you too are having a joy-filled weekend!
Seattle almost-summer day #hiking #rattlesnakeledg Seattle almost-summer day #hiking #rattlesnakeledge #seattle
I hope you have a joy-filled 2021! I hope you have a joy-filled 2021!
Breathing out of 2020 and into 2021. #hawaii #hiki Breathing out of 2020 and into 2021. #hawaii #hiking #awe #mindfulness
Instagram post 18137289235185551 Instagram post 18137289235185551
Instagram post 17851535831416158 Instagram post 17851535831416158
Instagram post 17889383257655934 Instagram post 17889383257655934
Ah... Ah...
Instagram post 17850799412251973 Instagram post 17850799412251973
www.newcancerinfo.com www.newcancerinfo.com
Exciting new research results... Exciting new research results...
#moma #manhattan #travelphotography #museumofmoder #moma #manhattan #travelphotography #museumofmodernart #cancerdoctor #barnard #newyork #newyorkcity #photography #leicaphotography #blackandwhitephotography #photographylovers #photooftheday
3 ways to lower your colon cancer risk #cancer#col 3 ways to lower your colon cancer risk #cancer#coloncancer#dietandcancer#rectalcancer#wellness#lifestyle
Love the early morning Pike Place Market. Peaceful Love the early morning Pike Place Market. Peaceful, as it opens.
#seattle#spaceneedle#pikeplacemarket#pacificnorthw #seattle#spaceneedle#pikeplacemarket#pacificnorthwest#travelphotography#leicaphotography
#finnriver #finnrivercider #finnriverfarm #PortTow #finnriver #finnrivercider #finnriverfarm #PortTownsend  #olympicpeninsula #BainbridgeIsland #seattlephotographer #travelphotography #cider  #appleciderfestival
#finnriver#olympicpeninsula #porttownsend #seattle #finnriver#olympicpeninsula #porttownsend #seattle #seattlelife #thingstodoinseattle #ciderfestival #ciderhouse #bainbridgeisland
#prostatecancer #cancer#prostate#cancer #wellness #prostatecancer #cancer#prostate#cancer #wellness #prostatecancerawareness #prostateexam #prostatecancerawarenessmonth #menshealth
Follow on Instagram

Footer

On the Blog

  • Body
  • Mind
  • Social

Info

  • About
  • Shop
  • Contact

stay in the know

Copyright © 2025 · Theme by 17th Avenue